Collaboration in health and social care has been a goal of

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Mast cell specific scFvs were identified which labelled mast cells but not Jurkat cells by flow cytometry. Of these, one scFv (A1) consistently inhibited mast cell adhesion to HASMCs and BEAS 2B epithelial cells by about 30 %. A1 immunoprecipitated Kit (CD117) from HMC 1 lysates and bound to a human Kit expressing mouse mast cell line, but did not interfere with SCF dependent Kit signalling.Conclusion: Kit contributes to human mast cell adhesion to human airway epithelial cells and HASMCs, but may utilise a previously unidentified adhesion domain that lies outside the SCF binding site.

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